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Although this mechanism by which zonulin dysregulates tight junctions has been well described thus far, it is important to note the controversy around EGFR localization within the apical membrane of intestinal epithelial cells and the implications this controversy may have on this specific mechanism

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These nucleifastigial, dentate, globose, and emboliformconstitute the principal output hubs, projecting to motor, sensory, limbic, and associative regions, thereby linking the cerebellum to both motor and non-motor functions (3538)

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