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Bielecka-Wajdman AM, Ludyga T, Smyk D, Smyk W, Mularska M, widerek P, et al

Pharmacological targeting of cell necroptosis/ferroptosis could promote cell adaptive repair and improve fibrosis

Overview IGF-DES is classified as a potent IGF-1 variant that appears to exhibit approximately 10-fold greater bioactivity than full-length IGF-1 in certain assays due to its reduced affinity for IGFBPs

Although LMNA (WT) has no differences to non-transgenic AB(WT) control, the LMNA mutant transgenic fish, particularly those with LMNA (L35P), LMNA (E358K), LMNA (R453W), and LMNA (A539V) variants, displayed significantly reduced muscle fiber diameters compared to LMNA (WT) group