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A plausible mechanism of action in these cases may be nicotine acting as an anti-inflammatory agent, and interfering with the inflammation-related disease process, as nicotine has vasoconstrictive effects

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However, a one-to-one translation of tobacco control strategies to reducing alcohol use may not be entirely possible since tobacco is highly addictive, the mechanisms of addiction may be different from alcohol, and most mainstream tobacco control interventions typically advocate for complete cessation (32)

A nod from the FDA would give 22nd Century a useful marketing tool that Marlboro maker Altria lacks