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Results by dose group: Two things stand out

GGT activity was calculated by obtaining the slope of the linear range of each sample (Abs per min) and dividing by the slope of a 4-nitroaniline standard curve (Abs per nmoles pNA) and by the protein mass (mg) to determine the reaction rate of the sample (nmoles pNA min 1 mg 1 )

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Histologically, IPF is defined by the usual interstitial pneumonia (UIP) pattern, characterized by patchy fibrosis, fibroblastic foci, and honeycombing ( 1.3 Ferroptosis and IPF Ferroptosis, a unique form of cell death derived by iron overload and lipid peroxidation, has emerged as a critical contributor to oxidative stress and chronic inflammation in IPF