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Cadenas C, Franckenstein D, Schmidt M, Gehrmann M, Hermes M, Geppert B, et al

R., Frederick, P

however, approximately 25% of patients who receive tretinoin for the treatment of APL have experienced acute promyelocytic leukemia differentiation syndrome

Thiol-disulfide exchange reactions between the catalytically active domains of PD-I and cysteines of nascent client proteins could result in rupture, creation, or isomerization of disulfide bonds