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Typical applications include: Obesity and Body-Weight Regulation Models : Studying how chronic AOD 9604 exposure affects body weight, fat, and energy expenditure in obese rodents, often using indirect calorimetry and body composition analyses

The decision to continue or stop biologic agents should be individualised, taking into account alternative therapies, the severity of the mothers condition prior to therapy, the risk of disease flares caused by treatment cessation and the impact of a flare on the mother and the unborn child[1,116]

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The rats were purchased from Universiti Sains Malaysia's Animal Research and Service Centre (ARASC) in Penang, Malaysia