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DNA Damage response signaling pathways and targets for radiotherapy sensitization in cancer

Pb 2+ also activates the synthesis and secretion of the proinflammatory cytokine IL-8 through a nuclear factor erythroid 2-related factor 2 (Nrf2)-dependent mechanism involved in the synthesis of xenobiotic-metabolizing enzymes (Metryka et al

It was built around a single topical peptide called OS-01 that helps to remove senescent cells from the body, also known as zombie cells, which are no longer functioning properly and create inflammation