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Notably, elevated levels of pro-inflammatory cytokines, such as interleukin-1beta(IL-1), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-), and interferon-gamma (IFN-), have been consistently observed in patients with ME/CFS [33, 34]

Therefore, if epitalon binds to and inhibits H1.3 in the cancer cells, H19 would be derepressed

doi: 10.1093/toxsci/kfh042 84 GuilletteLJCrainDARooneyAAPickfordDB

DCA accumulates in high-fat diet-induced colitis models, polarizing macrophages toward M1 phenotypes via TLR2 to increase proinflammatory cytokines (372)