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To this end, we developed an in-silico approach combining both unbiased identification of transcriptional signatures associated with oligodendroglial formation (i.e., transcriptomes) and knowledge-driven curation of transcriptional changes associated with oligodendrogenesis (i.e., OligoScore)

extract on acetaminophen-induced hepatotoxicity

Some of these were ones we personally observed while on deep-sea missions

In this approach, NO is generated from the donor compound 3-(2-hydroxy-1-methyl-ethyl-2-nitrosohydrazino)-N-methyl-1-propanamine, which is oxidized to NO2 by the target compound 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (carboxy-PTIO)