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A list of common conditions besides pernicious anemia associated with a B12 deficiency includes the following: Crohns disease Celiac disease Atrophic gastritis, otherwise known as a thinning of the stomach lining Bacteria or parasites in the intestines Immune system disorders, including Graves disease and lupus Inflammatory bowel disease (IBD) Medications Medications can also interfere with B12 absorption, such as some heartburn medicines and proton pump inhibitors prescribed to diabetics

this occurs because there is not enough vitamin B12 in the diet, or poor absorption Pernicious anemiaa type of megaloblastic anemia caused by a lack of intrinsic factor, so that vitamin B12 is not absorbed Fatigue, weakness Nerve damage with numbness, tingling in the hands and legs Memory loss, confusion Dementia Depression Seizures Up to 15% of the general population has a B12 deficiency