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Live imaging microscopy of adipocytes transduced with an Akt sensor (FoxO1-Clover) demonstrated that FoxO1 translocation from the nucleus to the cytosol was reduced, indicting less Akt activation in Mg 2+ -deficient adipocytes

Under diabetic conditions, DAG accumulation occurs through multiple pathways

Therapeutic potential of superoxide dismutase mimetics as therapeutic agents in critical care medicine

This is particularly intriguing, as the recent work uncovered that U1-snRNP may serve as a governing machinery for blocking premature polyadenylation 48 , suggesting FUS/TLS might play an important role in regulating polyadenylation selection