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Hierarchical clustering of commonly engaged proteins by the fold increase in target engagement in senescent versus non-senescent conditions (referred to as senescence selectivity) identified broadly highly-reactive proteins, clusters of proteins with specificity to certain chemotypes and others (such as GPX4) that were enriched in probes related to three different SCLAs (Fig

The Interleukin-6 cytokine system regulates epidermal permeability barrier homeostasis

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Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease