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10.3389/fchem.2015.00027 76 CoppedF

Grapefruit fruit inhibits CYP3A4 check with clinician before any internal use if on statins, calcium-channel blockers, or other CYP3A4-cleared drugs

Further studies of the PNPLA3 polymorphism in the context of NASH in humans and its mechanism of action are required, to confirm whether murine models with this genetic mutation are good preclinical models of NASH