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5f) 65,66,67,68

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Although the importance of the potential interaction between IGF-1 signaling and MUSA1, SMART, Nedd4, Trim32, and TRAF6 in skeletal muscle hypertrophy and atrophy remains to be determined, IGF-1 signaling pathway components could be novel targets to regulate these E3 ubiquitin ligase activities in skeletal muscle

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PMID 16168066

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Week 1 to 4: Initial adaptation

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