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It is important to recognize that the establishment of reference intervals is influenced by several factors, including population characteristics, geographical variations, and testing methodologies [21, 22]

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Considering these factors, we proposed to require that hospitals report on the Medicare cost report the median payer-specific negotiated charge that the hospital has negotiated with all of its MAO payers, by MS-DRG, effective for cost reporting periods ending on or after January 1, 2026, and to use this data in a new market-based MS-DRG relative weight methodology, beginning in FY 2029