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J Biol Chem (1985) 260(2):7827

The importance of nonaxonal pressure targets was accentuated in a landmark study by Morgans group, which demonstrated that pressure-induced dendritic retraction and RGC loss occur in the presence of intact axons (62)

Patients receiving Idebenone also had a greater mean reduction in fibrosis 4 (FIB-4) scores after 48 weeks (a Wilcoxon rank-sum test demonstrated that the mean difference was statistically significant, p = 0.0473)

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