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Similarly to hypertension, coronary artery disease, and cancer, allergies have been classified as lifestyle diseases ( Numerous epidemiological and clinical studies have shown that oxidative stress directly or indirectly contributes to the risk of lifestyle diseases ( - ), the strongest oxidizing agent in vivo ( According to recent research, oxidative and nitrosative stress plays a key role in the pathogenesis of respiratory (including asthma) and skin allergies (AD, urticaria) ( st century, which is why the role of oxidative, nitrosative and carbonyl stress in selected atopic diseases should be carefully scrutinized

379 Current researches have demonstrated that the mechanisms of systemic IR and brain-specific IR have close links with AD pathogenesis

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The utilization of human cells, including iPSCs, raises ethical questions related to the source of cells, their derivation, and potential risks [45, 737]