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doi: 10.1172/JCI40104 75 GadilaSKGRosoklijaGDworkAJFallonBAEmbersME

In normal endometrium, progesterone antagonizes estrogen-mediated growth

In contrast to this human-specific mechanism, previous murine models had reported that GBPs promote inflammasome activation through vacuolar disruption, which facilitates bacterial escape and direct bacteriolysis (Meunier et al., 2014