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Kruidenier L, Kuiper I, et al

When NNMT is overactive, it depletes key metabolic molecules and reduces NAD+ availability both associated with increased fat storage and metabolic dysfunction

As the second leading cause of adult-onset sensorineural deafness (Mathers et al., 2000), noise-induced hearing loss (NIHL) is a preventable condition that represents a large worldwide economic burden, as well as a health priority (World Health Organization, 1997, 2018