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doi: 10.1164/ajrccm.162.5.9910066 91 LuXZhangAWangHXuXChenLLuoL

The presence of DTT-cysteine adducts at C41 and C108 are perhaps counter-intuitive, as C110 is implicated as the major site of protein cross-linking 25

10.1007/s11306-016-1147-x 291 WeiX.LiL

2.10 Overexpression and knockdown of RRM2 gene in TPC-1 and IHH4 cells For upregulating RRM2 expression in cells, we obtained a full-length RRM2 sequence fragment using a PCR method and subsequentlycloned it into vector LV18, verified by DNA sequencing and transfected 293T cells (see Supplementary Materials for details)