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In recent years, there is sufficient evidence that oxidative stress and inflammation are also important pathological mechanisms of HE, and ammonia jointly promote the occurrence and development of HE

The nod, which converts a November 2022 accelerated approval, makes Elahere the first and only antibody-drug conjugate (ADC) approved in the U.S. for ovarian cancer, Roopal Thakkar, AbbVies CMO of global therapeutics, said in a statement

In fact, the gut microbiota can regulate glucose metabolism by regulating the interaction between BAs and FXR and TGR5 signaling [112]

conducted a large, population-based longitudinal cohort study, establishing a link between increased TG levels and a heightened risk of depression ( Figure 1E ), in individuals with major depression