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141 The same combination of CoQ10 and selenium was also found to reduce levels of von Willebrand factor and tissue plasminogen activator inhibitor-1, molecules with critical roles in promoting thrombosis, in another four-year placebo-controlled trial in 308 elderly individuals with low selenium status

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Other peptides under investigation Several additional peptides are being studied for disc-related applications, though with less established evidence: Vasoactive Intestinal Peptide (VIP) has demonstrated the ability to slow disc degeneration progression and improve aggrecan levels in mouse studies

While these methods help many patients, a significant percentage continue struggling with chronic pain that limits their quality of life for months or even years