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During recent decades, researchers turned to delivery systems based on natural and synthetic polymers and lipids because such liposomes possess valuable qualities, such as the incorporation of hydrophilic and hydrophobic drugs, and membrane penetration ( Application of Exosomes Providing a Novel View for Ferroptosis-Based Cancer Treatment Modified exosomes can be selectively used to deliver drugs to specific cells and present advantages, such as high effectiveness and reduced toxicity

Kumar GA, Chattopadhyay A (2020) Statin-induced chronic cholesterol depletion switches GPCR endocytosis and trafficking: insights from the serotonin(1A) receptor

The selective inhibitor of the lipid kinase PI3K idelalisib (NCT01539512) promotes apoptosis in primary CLL cells, and disrupts interactions between CLL cells and endothelial cells/bone marrow stromal cells [119, 120]

We thus have systematically collected all relevant RCTs, and our results suggested that ALC is effective and safe for alleviating pain of PNP patients