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In a 48-week phase 2 trial published in The New England Journal of Medicine , adults with obesity (without type 2 diabetes) receiving once-weekly subcutaneous retatrutide at the 12 mg amount achieved a least-squares mean body weight reduction of 24.2%, compared with 2.1% in the placebo group [1]

Below, we break down the details from notable pieces of research, including the outcomes of a few completed clinical (human) trials

From a GHK-Cu safety perspective, FDA drug approval requires comprehensive toxicological evaluations covering specific populations, long-term continuous exposure, and different administration routes

doi: 10.1016/j.nutres.2021.05.008 229 RasiaR