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112 DAN encompasses multiple subtypes, including cardiovascular autonomic neuropathy (CAN), gastrointestinal autonomic neuropathy, genitourinary autonomic neuropathy, sudomotor dysfunction, hypoglycemia unawareness, and pupillary dysfunction, each affecting different organ systems and presenting a spectrum of clinical manifestations

Pure, natural fat such as: butter, mayonnaise, olive oil, safflower, sunflower and other vegetable oils (expeller-pressed or cold-pressed is recommended)

Ethics declarations Ethics approval and consent to participate Patients from CNIC provided written informed consent and the protocol was approved by the Ethics Committee of Hospital Carlos III (internal code P2/12)