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The NLX-precipitated withdrawal phenomena (except for the sneezing) were diminished in rats that had received fentanyl + L-NAC, and more greatly diminished in rats that had received fentanyl + L-NACme

These phytochemicals can interact with different types of receptors in the central nervous system (CNS), such as N-methyl-D-aspartate receptor (NMDAR), Gamma-aminobutyric acid receptor (GABAAR), and -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR), channels like voltage gated sodium, potassium, and calcium channels, and other enzymes and pathways that play a significant role in the initiation and propagation of epileptic seizures