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These include: Hemodialysis Hemodialysis also often involves blood transfusion and/or administration of erythropoietin or its analogs either of which also require a TUE Treatment for Sickle Cell Disease involves homologous blood transfusions which are prohibited If an athlete requires a Prohibited treatment involving the removal and reintroduction of blood into the circulation for any legitimate medical condition, they should apply for a Therapeutic Use Exemption (TUE) before undergoing the treatment

on alternate days until there is no further improvement

This metabolic safety profile expands the potential population who might safely use the peptide under medical supervision

In a phase Ib study (NCT02283775) of isatuximab-Pd administered by a fixed infusion volume, 7 of 47 patients had received daratumumab in a prior line [58]