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7 Therapeutic strategies and clinical translation With the deepening understanding of ferroptosis mechanisms, an increasing number of molecular targets have been identified as closely associated with the pathological progression of AD

By increasing the lifespan of these cells, IGF-1 helps to increase their number with muscle tissue

Proline dehydrogenase/proline oxidase-dependent apoptosis/autophagy may be modulated by the interconversion of glutamate, ornithine, and proline, among which proline is the key amino acid (98)