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Overall, targeting mitophagy in PDAC holds promise, but clinical translation will require pathway-specific insights, selective modulators, advanced delivery strategies, and effective patient stratification

The importin :Ran-GTP complex was formed by incubating importin and Ran-GTP at 14 molar ratio at 4 C for 30 min

Another study found that N-acetylcarnosine decreased lens cell telomere shortening to protect against oxidative stress (75,136) and the harmful effects of lipid peroxides on the crystalline lens in vivo (137)