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caldus strains grown for 7 days without heavy metals were supplemented with CuSO 4 (final concentration: 5 mM) or ZnSO 4 (final concentration: 40 mM), respectively, incubated at 40C and shaken at 150 rpm

Circulation 2004;109(21 Suppl 1):II34-II41

One of the mechanisms of lithium is to inhibit inositol phosphatase and thus reduce intracellular levels of inositol, a simple isomer of glucose that acts as a precursor to the second messenger system coupled to cholinergic, serotonergic, and adrenergic neurotransmitter systems