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2.3 Extraction of curcuma compounds and statistical analysis The SFE + UAE sequential extraction was studied using the residue from the supercritical fluid extraction step (that provided the highest volatile oil extraction yield) as a biomass for the UAE step (Figure 1)

however, while systolic function can improve with treatment, no significant reverse remodeling occurs 2

doi: 10.1016/j.matbio.2015.01.015 74 KimuraYYanagidaTOndaATsukuiDHosoyamadaMKonoH

Introduction With the huge burden of neurological diseases on patients life and society resources, the need of finding and having neuroprotective agents is critical and cost-effective