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B12 is a cofactor in metabolic pathways that convert food into usable energy (ATP), which has led to the misconception that it acts as a stimulant

However, some individuals may struggle to obtain sufficient amounts of B12 from their diet, leading to a deficiency

NCBI-Study For someone already on a GLP-1 drug whos plateaued or not losing enough weight, tirzepatide can offer an advantage because of its dual-hormone action (GLP-1 + GIP), which seems to enhance satiety, reduce food intake, improve metabolic efficiency, and often results in greater absolute weight loss