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Heat-killed bifidobacterium bifidum B1628 may alleviate dextran sulfate sodium-induced colitis in mice, and the anti-inflammatory effect is associated with gut microbiota modulation

The nature of this ROS signal was H 2 O 2 , as it was detected by the H 2 O 2 specific PF1 probe (Supplementary Figure S6A), and its cellular origin the ER, as suggested its disappearance upon UPR prevention by Ire1 kinase inactivation (Figure 4F, lower)

Aleksandrova, K., Koelman, L., & Rodrigues, C