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10.1038/srep35613 307 YaoH.-W.LingP.TungY.-Y.HsuS.-M.ChenS.-H

FIGURE 3 One potential minor drawback of exogenous cytoplasmic PC expression is the activation of another metabolically futile cycle, with PC functioning together with phosphoenolpyruvate carboxykinase 1 (PCK1) and pyruvate kinase (PKM) to futilely hydrolyze GTP to GDP (Figure 3A), which could inhibit GTP-dependent processes such as endocytosis and autophagy (Santana et al., 2025)

This guy on Reddit just dropped a 57-page Google Doc summarizing peptides like BPC-157, and all the human trials that have been done so far Link below