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Unwinding of the 3X tail by HCV NS3h is a tempting model, and our data provide a hint towards distinct functions of viral helicases in the initiation of negative-strand synthesis

Berberine significantly reduces hepatic MDA and MPO levels, inhibits JNK phosphorylation and upregulates the expression of Nrf-2 in the nucleus and its downstream gene Mn-SOD

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Cheng S, Sliva D