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Complementary approaches like surface charge neutralization, PEGylation modifications, or Fc-region fusion could further enhance serum half-life while mitigating ADA responses 36,37

This wide-ranging influence on various biological processes and organ systems is often described as a "pleiotropic" effect, signifying its ability to produce multiple distinct and beneficial outcomes

When searched in PubMed with the search terms A-peptide and oxidative stress and Alzheimer disease mouse models, 467 articles were retrieved