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Sensitivity of Prx II-knockdown HaCaT cells to H 2 O 2 cytotoxicity Efficacious knockdown of the Prx II gene in HaCaT cells required successful intracellular vector transfer

Although thioredoxin is not itself imported into the ER (being an 11.6 kDa protein rather than a small tripeptide like glutathione), the pathway has been shown to influence ER lumenal redox potential, likely through the conveyance of reducing equivalents through an as-yet unknown ER-resident transmembrane protein (Poet et al., 2017)

The reactions were carried out on a digital PCR machine (D3200)

Oxidative stress plays significant roles in cancer, but also Atherosclerosis, Arthritis, and cataracts