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Description

Results from drugdrug interaction studies in vitro and in vivo investigating the inhibitory effect of finerenone on the drug transporters bcrp, oatp1b1, and oatp1b3

At 0.25 mg per unit, 4 units = 1 mg and 8 units = 2 mg

Studies have shown that exposure to DEHP may affect estrogen metabolism and signal transduction 20,26 , and that abnormal estrogen levels or disordered estrogen signaling pathways increase the risk of BRCA 27

The company positions the approach as a more accessible alternative for patients who are candidates for isotretinoin therapy but may be hesitant to pursue the oral formulation, including women of childbearing potential