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ROS further modulate the nuclear factor kappa B (NF-B) pathway (Lingappan, 2018) and induce oxidative modifications of transcription factors (e.g., Nrf2, p53), altering their stability and activity in cancer-related processes (Humpton et al., 2022)

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In neurodegenerative diseases like Alzheimers and Parkinsons, antioxidants may help protect neurons from oxidative damage and slow disease progression [199]