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Czekaj R, Majka J, Ptak-Belowska A, et al

This work [170], together with a clinical trial of gene therapy for adrenoleukodystrophy [175], constituted the first trial of the use of a LV for the treatment of an inborn genetic disease to be approved anywhere in the world

Optimizing protocolsthrough tailored selection of stimulation parameters, electrode montage, and dosing schedulesrequires mechanistic insight and careful consideration of patient-specific features