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Kankofer M, Wawrzykowski J, Giergiel M

Combined therapy that involves the inhibition of Gln metabolism alongside PD-L1 blockade has been shown to enhance the anti-tumor immune response of T cells ( in vivo and in vitro ( DON, which exhibits high structural similarity to Gln, enhances the cytotoxic effects of CD8+ T cells while inhibiting Gln metabolism in cancer cells

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(2017) reported a significant increase oxidative stress related biomarkers (protein carbonyls and advanced glycation end products) in both aqueous humor and blood samples from glaucoma patients, compared to healthy subjects (Hondur et al., 2017)