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5.3 Controlled drug release Controlled drug release can prevent premature drug degradation and systemic exposure, enabling precise drug delivery at the target site while maintaining stable local concentrations and minimizing resistance escape

In primates, TM supports ~80-90% of aqueous outflow and thus represents the principal bottleneck for fluid outflow whereas the auxiliary uveoscleral outflow pathway in the ciliary muscle (#1 in Figure 6A) supports the rest

Beyond our expectations, we found a positive correlation between PSPH and galectin-1 expression in patients with GBM undergoing anti-PD1 treatment