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Description

The role of gremlin, a BMP antagonist, and epithelial-to-mesenchymal transition in proliferative vitreoretinopathy

J1999 3

When phospholipid membranes rich in polyunsaturated fatty acids (PUFAs) undergo excessive peroxidation due to Fe 2+ activation, and antioxidant defenses are overwhelmed, iron accumulates, triggering ferroptosis ( Several key steps in lipid oxidation contribute to the initiation of ferroptosis