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2.1 Generation of 1 C units One-carbon units are generated through multiple interconnected metabolic pathways, including serine and glycine metabolism, the glycine cleavage system (GCS), and the catabolism of histidine and tryptophan (Fig

In comparing CC with DC, decompensation is significantly associated with worsening components of SF-36 including PCSS (MD of 6.79, 95% CI of 4.54 to 9.05, random effect, I2 = 87%, P 18.3)