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Salminen S, Collado MC, Endo A, et al

10.1001/archfami.9.8.722 61 MacyE

Elevated levels of IGFBP-2 in the bloodstream are linked to significant brain atrophy, extensive gray matter volume loss, and decreased FDG metabolism in the frontal, temporal, and occipital lobes of patients with AD [151, 154]