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While IL-17 alone does not inhibit pigmentation, it significantly amplifies the inhibitory effect of TNF on melanin synthesis through a synergistic interaction (Wang et al., 2013)

This high metabolic rate leads to increased production of reactive oxygen species (ROS) as byproducts of cellular respiration.Presence of Redox-Active Metals: The brain contains transition metals such as iron and copper, which can catalyze the formation of highly reactive hydroxyl radicals through the Fenton reaction.Limited Regenerative Capacity: Unlike some other tissues, neurons have limited regenerative capacity

Reishi mushroom The immunomodulatory and antitumor effects have been associated with Reishi fermented mushroom (Rubel et al., 2018) (Fig

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