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The use of 2-deoxy-4-thiocytidine and its analogues as DNA hypomethylating anticancer agents

4613-C CLINICAL, GENETIC, AND PATHOLOGIC FEATURES, TREATMENT, AND LONG-TERM OUTCOME IN PATIENTS WITH BENIGN RECURRENT INTRAHEPATIC CHOLESTASIS: A MULTICENTER STUDY IN JAPAN Ken Kato 1 , Shuichiro Umetsu 2 , Takao Togawa 3 , Koichi Ito 3 , Takayoshi Kawabata 4 , Teruko Arinaga-Hino 1 , Naoya Tsumura 1 , Ryosuke Yasuda 1 , Yutaro Mihara 1 , Hironori Kusano 1 , Shogo Ito 3 , Kazuo Imagawa 5 , Hisamitsu Hayashi 6 , Ayano Inui 2 , Yushiro Yamashita 1 and Tatsuki Mizuochi 1 , (1)Kurume University School of Medicine, (2)Saiseikai Yokohamashi Tobu Hospital, (3)Nagoya City University Graduate School of Medical Sciences, (4)Ishikawa Prefectural Central Hospital, (5)University of Tsukuba, (6)The University of Tokyo Background: There have been few reports of benign recurrent intrahepatic cholestasis (BRIC) from East Asia

Following adjustment for demographic variables, the association between nutrient intake and depressive symptoms was found to vary according to cultural background

It creates a chronic pro-oxidant environment that overwhelms the already-depleted GSH-based antioxidant network in diabetic patients