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Nevertheless, it is worth to notice that neither everolimus nor temsirolimus seem to be selective for all cancer cell lines as EGCG, resveratrol or curcumin (209)

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In addition to insulin resistance, patients with CKD often experience hyperparathyroidism, vitamin D deficiency, and low levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) (76, 77)