liposomal glutathione oral bioavailability evidence randomized trial outperforms plain glutathione in uptake, cell regeneration and systemic availability: from cellular and human models Oral supplementation with liposomal glutathione

Convolvulus pluricaulis extract is one of the most widely used neuropharmacological agent that significantly improved learning and memory in experimental models 34,51,52

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When RBMS1 was ablated, SLC7A11 translation was inhibited and ferroptosis was induced [78]

Abbreviations 1 O 2 : Singlet oxygen ADP: Adenosine diphosphate AOX: Alternative oxidase APX: Ascorbate peroxidase Asc: Ascorbate ATP: Adenosine triphosphate cat : Catalase knockout CAT: Catalase chl- E : GSH Chl-roGFP oxidation state chl-roGFP2: Chloroplast targeted roGFP CLSM: Confocal-laser scanning microscopy cry: Cryptochrome DTT: Dithiotreitol E : h Reduction potential ER: Endoplasmic reticulum FIN219: Far-Red Insensitive 219 FIP1: FIN219-interacting protein 1 GGT-1: Gamma-glutamyl transferase/transpeptidase 1 ggt : GGT-1 knockout GR: Glutathione reductase GSH: Reduced glutathione GSHS: Glutathione synthetase GSSG: Oxidized glutathione (= glutathione disulfide) GSSG/GSH: Reduction state of glutathione GT: Glutathione transferase H 2 O 2 : Hydrogen peroxide HPLC: High performance liquid chromatography HyPer2: Fluorescent H 2 O 2 biosensor IgG: Immunoglobulin G immunolabeling: Total glutathione localization by use of a specific antibody LEDs: Light-emitting diodes mbrB: Monobromobimane mchlB: Monochlorobimane NADP + : Nicotinamide adenine dinucleotide phosphate NADPH: Reduced form of NADP + NEM: N-ethylmaleimide O 2 : Superoxide radicals pad : Phytoalexin deficient phyA: Phytochrome A PS II: Photosystem II roGFP: Redox-sensitive green fluorescence protein ROS: Reactive oxygen species SOD: Superoxide dismutase TEM: Transmission electron microscope Total glutathione: Sum of reduced (GSH) and oxidized (GSSG) glutathione, detected via immuno-labeling vtc : Vitamin C1 gene -EC: -Glutamylcysteine -ECS: -Glutamylcysteine synthetase References Appolloni E, Pennisi G, Zauli I, Carotti L, Paucek I, Quaini S, Orsini F, Gianquinto G (2022) Beyond vegetables: effects of indoor LED light on specialized metabolite biosynthesis in medicinal and aromatic plants, edible flowers, and microgreens