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Accordingly, a hallmark of infection with CMV and other herpesviruses is the continuous expansion and maintenance of a large pool of virus-specific, functional CD8+ effector memory T cellsa phenomenon termed memory T cell inflation 23,24 that correlates to CMV control and latency 25

The initial SARS-CoV-2 viral infection triggers an immune response that may persist in some individuals even after the virus has been cleared, leading to ongoing hyper-inflammation

The SNR was calculated as the ratio of the maximum signal, in the range of 0.5 to 4.2 ppm, minus the baseline to two times the root mean square of residuals, as reported by LCModel